| # | Player | Pos | Team | G | Pass yds | Pass TD | Rush yds | Rush TD | Rec | Rec yds | Rec TD | Sacks | Tackles | FP (PPR) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Jalen Hurts | QB | PHI | 16 | 3,224 | 25 | 421 | 8 | 301.1 | |||||
| 2 | Saquon Barkley | RB | PHI | 16 |
| 1,140 |
| 7 |
| 37 |
| 273 |
| 2 |
| 1 |
| 232.3 |
| 3 | A.J. Brown | WR | PHI | 15 | 78 | 1,003 | 7 | 220.3 |
| 4 | DeVonta Smith | WR | PHI | 17 | 77 | 1,008 | 4 | 201.8 |
| 5 | Dallas Goedert | TE | PHI | 15 | 60 | 591 | 11 | 2 | 185.1 |
| 6 | Tank Bigsby | RB | PHI | 15 | 356 | 2 | 3 | 32 | 1 | 53.8 |
| 7 | Jahan Dotson | WR | PHI | 15 | 18 | 262 | 1 | 50.2 |
| 8 | Grant Calcaterra | TE | PHI | 9 | 9 | 76 | 1 | 1 | 22.6 |
| 9 | Will Shipley | RB | PHI | 14 | 49 | 9 | 56 | 7 | 19.5 |
| 10 | Darius Cooper | WR | PHI | 6 | 9 | 92 | 18.2 |
| 11 | Tanner McKee | QB | PHI | 4 | 274 | 1 | 8 | 13.8 |
| 12 | Kylen Granson | TE | PHI | 12 | 7 | 40 | 10 | 11.0 |
| 13 | AJ Dillon | RB | PHI | 6 | 60 | 3 | 21 | 1 | 9.1 |
| 14 | Jordan Davis | DT | PHI | 17 | 4.5 | 32 | 6.0 |
| 15 | Sydney Brown | SAF | PHI | 15 | 17 | 6.0 |
| 16 | Britain Covey | WR | PHI | 6 | 2 | 20 | 4.0 |
| 17 | Xavier Gipson | WR | PHI | 6 | 2 | 6 | 1 | 2.6 |
| 18 | Brandon Graham | DE | PHI | 4 | 3 | 4 |
| 19 | Charley Hughlett | LS | PHI | 2 | 1 |
| 20 | Lane Johnson | OT | PHI | 4 | 1 |
| 21 | Za'Darius Smith | DE | PHI | 4 | 1.5 | 3 |
| 22 | Jake Elliott | K | PHI | 17 | 1 |
| 23 | Adoree' Jackson | CB | PHI | 13 | 40 |
| 24 | Parry Nickerson | CB | PHI | 1 | 2 |
| 25 | Jordan Mailata | OT | PHI | 5 |
| 26 | Fred Johnson | OT | PHI | 3 |
| 27 | Marcus Epps | SAF | PHI | 9 | 18 |
| 28 | Brett Toth | G | PHI | 3 |
| 29 | Joshua Uche | LB | PHI | 11 | 1 | 13 |
| 30 | Zack Baun | LB | PHI | 16 | 3.5 | 63 |
| 31 | Michael Carter II | CB | PHI | 7 | 9 |
| 32 | Azeez Ojulari | LB | PHI | 2 | 2 |
| 33 | Patrick Johnson | LB | PHI | 5 | 1 | 5 |
| 34 | Jaelan Phillips | LB | PHI | 17 | 5 | 27 |
| 35 | Landon Dickerson | G | PHI | 5 |
| 36 | Reed Blankenship | SAF | PHI | 16 | 53 |
| 37 | Cal Adomitis | LS | PHI | 1 | 1 |
| 38 | Nakobe Dean | LB | PHI | 9 | 4 | 30 |
| 39 | Cam Jurgens | C | PHI | 4 |
| 40 | Jalen Carter | DT | PHI | 12 | 3 | 19 |
| 41 | Moro Ojomo | DT | PHI | 17 | 6 | 17 |
| 42 | E.J. Jenkins | TE | PHI | 1 |
| 43 | Cameron Latu | TE | PHI | 10 | 7 |
| 44 | Byron Young | DT | PHI | 14 | 2.5 | 11 |
| 45 | Tyler Steen | OT | PHI | 7 |
| 46 | Nolan Smith | LB | PHI | 12 | 3 | 15 |
| 47 | Jakorian Bennett | CB | PHI | 3 | 5 |
| 48 | Kelee Ringo | CB | PHI | 14 | 28 |
| 49 | Andre' Sam | SAF | PHI | 1 | 1 |
| 50 | Jalyx Hunt | LB | PHI | 17 | 6.5 | 27 |
| 51 | Jeremiah Trotter Jr. | LB | PHI | 13 | 14 |
| 52 | Cooper DeJean | CB | PHI | 16 | 63 |
| 53 | Quinyon Mitchell | CB | PHI | 16 | 35 |
| 54 | Smael Mondon Jr. | LB | PHI | 8 | 4 |
| 55 | Brandon Johnson | CB | PHI | 2 | 1 |
| 56 | Mac McWilliams | CB | PHI | 2 | 1 |
| 57 | Ty Robinson | DT | PHI | 3 | 1 |
| 58 | Jihaad Campbell | LB | PHI | 16 | 42 |
| 59 | Andrew Mukuba | SAF | PHI | 11 | 0.5 | 24 |
| 60 | Braden Mann | P | PHI | 17 | -34 | -3.4 |
