| # | Player | Pos | Team | G | Pass yds | Pass TD | Rush yds | Rush TD | Rec | Rec yds | Rec TD | Sacks | Tackles | FP (PPR) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Kenneth Gainwell | RB | PIT | 17 | 537 | 5 | 73 | 486 | 3 | 3 | 221.3 | |||
| 2 | Jaylen Warren | RB | PIT | 16 | 958 | 6 | 40 | 333 | 2 | 217.1 | ||||
| 3 | Kaleb Johnson | RB | PIT | 10 | 69 | 1 | 9 | 8.8 | ||||||
| 4 | Trey Sermon | RB | PIT | 3 | ||||||||||
| 5 | Lew Nichols III | RB | PIT | 1 |
