| # | Player | Pos | Team | G | Pass yds | Pass TD | Rush yds | Rush TD | Rec | Rec yds | Rec TD | Sacks | Tackles | FP (PPR) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Jonathan Taylor | RB | IND | 17 | 1,585 | 18 | 46 | 378 | 2 | 1 | 362.3 | |||
| 2 | Ameer Abdullah | RB | IND | 13 | 60 | 1 | 16 | 99 | 5 | 37.9 | ||||
| 3 | DJ Giddens | RB | IND | 5 | 96 | 9.6 | ||||||||
| 4 | Tyler Goodson | RB | IND | 10 | 24 | 2 | 8 | 6 | 5.2 | |||||
| 5 | Ulysses Bentley IV | RB | IND | 1 |
