| # | Player | Pos | Team | G | Pass yds | Pass TD | Rush yds | Rush TD | Rec | Rec yds | Rec TD | Sacks | Tackles | FP (PPR) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | James Cook | RB | BUF | 17 | 1,621 | 12 | 33 | 291 | 2 | 302.2 | ||||
| 2 | Ty Johnson | RB | BUF | 17 | 200 | 3 | 24 | 263 | 2 | 1 | 100.3 | |||
| 3 | Ray Davis | RB | BUF | 17 | 275 | 10 | 86 | 2 | 64.1 | |||||
| 4 | Reggie Gilliam | FB | BUF | 11 | 4 | 2 | 24 | 6 | 4.8 |
