| # | Player | Pos | Team | G | Pass yds | Pass TD | Rush yds | Rush TD | Rec | Rec yds | Rec TD | Sacks | Tackles | FP (PPR) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | DaQuan Jones | DT | BUF | 12 | 3 | 10 | ||||||||
| 2 | Jordan Phillips | DT | BUF | 8 | 1 | 5 | ||||||||
| 3 | Joey Bosa | DE | BUF | 15 | 5 | 17 | ||||||||
| 4 | Larry Ogunjobi | DT | BUF | 8 | 10 | |||||||||
| 5 | Ed Oliver | DT | BUF | 3 | 3 | 9 | ||||||||
| 6 | A.J. Epenesa | DE | BUF | 15 | 2.5 | 17 | ||||||||
| 7 | Greg Rousseau | DE | BUF | 16 | 7 | 23 | ||||||||
| 8 | Phidarian Mathis | DT | BUF | 5 | 4 | |||||||||
| 9 | Andre Jones Jr. | DE | BUF | 2 | 1 | |||||||||
| 10 | Zion Logue | DT | BUF | 2 | 0.5 | 1 | ||||||||
| 11 | Javon Solomon | DE | BUF | 12 | 1 | 11 | ||||||||
| 12 | Deone Walker | DT | BUF | 15 | 1 | 15 | ||||||||
| 13 | T.J. Sanders | DT | BUF | 10 | 1 | 7 |
